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Description
Human GP73, His tagProduct Specification Species Human Synonyms Golgi membrane protein GP73, Golgi phosphoprotein 2, GOLM2 Accession Q8NBJ4 Amino Acid Sequence Protein sequence(Q8NBJ4, Arg55 Leu401, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | Golgi membrane protein GP73, Golgi phosphoprotein 2, GOLM2 |
| Accession | Q8NBJ4 |
| Amino Acid Sequence | Protein sequence(Q8NBJ4, Arg55-Leu401, with C-10*His) |
| Expression System | HEK293 |
| Molecular Weight | Theoretical: 41kDa Actual: 65kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage |
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Background
Golgi protein-73 (GP73) is a type II Golgi-localized integral membrane protein that is normally expressed in epithelial cells of many human tissues. It is essential for human survival, and might have multiple roles for GP73 in epithelial cell function such as in the kidney and liver. GP73 has been suggested as a potential serum marker for the diagnosis of hepatocellular carcinoma (HCC)，Several reports have stated that GP73 is a better marker than AFP for diagnos ing HCC. Many studies have demonstrated that significant increases of non-viral causes (alcohol-induced liver dis ease, autoimmune hepatitis). Therefore, some researchers consider that an increase in GP73 expression is a common feature of hepatocyte response to a variety of disease etiologies.
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